Aplicaciones anidadas

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SWEET

 

Aplicaciones anidadas

Aplicaciones anidadas

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Sweeteners and sweetness enhancers: Impact on healthy, obestity, safety and sustainability

♦ Investigador principal: Prof. J. Alfredo Martinez

♦ Coordinador: University of Liverpool

♦ Call: H2020-SFS-2016-2017
Topic: SFS-40-2017
Grant Agreement: 774293

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Aplicaciones anidadas

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The SWEET project has been designed to:

i) identify and address the barriers and facilitators to the use of sweeteners and sweetness enhancers (S&SEs) and

ii) examine the risks and benefits of using S&SEs to replace sugar in the diet in the contexts of health, obesity, safety and sustainability. Industry experts will integrate technological, health and sweetness databases to provide a platform on which new and emerging S&SEs can be selected for inclusion in food products.

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The behavioural and physiological impact of specific S&SEs will be examined in acute and repeated dosing studies and natural population differences (by age, region, gender etc) in sweetness perception established. A sensory profile will be developed and genetic determinants assessed. The core randomised controlled trial will adopt a whole diet approach to examine the impact of prolonged sugar replacement on weight control, appetite and energy intake.

Underlying mechanistic effects of S&SE use, alone and in combination, will be evaluated using the technology platform developed in acute studies.

Outcomes relating to safety and overall health risks will be:

i) measured in acute and chronic studies and

ii)  investigated in secondary data (long term interventions, prospective cohorts).

The preferences for and perceptions of S&SEs within European consumers, and the barriers to their acceptance, consumption and use will be determined.

The environmental cost and sustainability of replacing sugar with S&SEs will also be modelled. Consumers will be engaged to inform research design, and stakeholder driven exploitation and impact plans will be developed to communicate and disseminate project objectives and results to:

i) address the role of sweeteners in weight control for target audiences (consumers, health professions, scientists, policy makers, regulators) and

ii) move effective products nearer to market.

A gender action plan will be developed and implemented to promote equity across all research activities.

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Overall objective: To examine the barriers & facilitators to the use of sweeteners & sweetness enhancers (S&SEs) & examine the likely risks & benefits of using them to replace sugar in the diet in the context of health, obesity, safety & sustainability.

Sub-objectives:

1. Select new & emerging S&SEs& blends, & through integration of technological expertise produce a range of innovative S&SE containing products of appeal to distinct demographics (e.g. age, region, gender).

2. Develop a platform of measures (e.g self-report, biological, cognitive, consumer questionnaires), including new tools, to examine the impact of replacing dietary sugar with S&SEs& validate against new urinary biomarker assays.

3. Determine the role of individual differences (both behavioural e.g. eating behaviour traits & biological e.g. taste receptor polymorphisms) in shaping food preferences & consumption patterns of distinct populations, & examine biological mechanisms underpinning these.

4. Assess the short term effect of specific S&SEs & blends & the prolonged impact of a whole diet approach on body weight, health, satiety, microbiota, biobehavioural processes & consumer perspectives & preferences.

5. Synthesise evidence from diverse European longitudinal data sets to examine the relationship between habitual S&SE use & obesity, health & safety in key geographic & demographic cohorts.

6. Examine the economic, environmental & social sustainability of replacing sugar with S&SEs across production, supply, consumption & waste (life cycle sustainability assessment) in the context of global supply chains using project case studies.

7. Assess the potential toxicology, allergencity & safety (microbiological, gastrointestinal (G.I.) side effects, microbiota & other adverse effects) of specific novel S&SE combinations & of the whole diet approach.

8. Review the regulatory barriers to innovation & tailor exploitation plans & dissemination accordingly.

Participant Name

Participant Organisation Name

Type

Country

1. Jason Halford

University of Liverpool (Co-ordinator)

RI

UK (GB)

2. Anne Raben

Kobenhavns Universitet

RI

Denmark (DK)

3. Douwina Bosscher

Cargill R&D Centre Europe

I

Belgium (BE)

4. Alfredo Martinez

University of Navarra

RI

Spain (ES)

5. Edith Feskens

Wageningen University

RI

Netherlands(NL)

6. Monique Raats

University of Surrey

RI

UK (GB)

7. Euan Woodward

European Association for the Study of Obesity

NPO

UK (GB)

8. Alain Lebail

Oniris

RI

France (FR)

9. Graham Finlayson

University of Leeds

RI

UK (GB)

10. Yannis Manios

Harokopio University

RI

Greece (GR)

11. Lluis Serra

Fundacio Privada per a la Investigacio Nutricional

RI

Spain (ES)

12. Mark Reed

University of Newcastle Upon Tyne

RI

UK (GB)

13. George Nychas

Agricultural University of Athens

RI

Greece (GR)

14. LoicBriand

InstitutNational de la RechercheAgronomoique

RI

France (FR)

15. Laetitia Gerbe

Tereos Participations

I

France (FR)

16. Santiago Ortega

CTAEX

SME

Spain (ES)

17. Martine Laville

CRNH Rhone-Alpes

RI

France (FR)

18. Torsten Sehlinger

Mobile Chamber Experts GmbH

SME

Germany (DE)

19. Ellen Blaak

Universiteit Maastricht

RI

Netherlands (NL)

20. Tony Lam

Netunion

SME

Switzerland (CH)

21. Helen Claringbould

Corepage

SME

Netherlands (NL)

22. Marine Boursier

Vitagora Pole

NPO

France (FR)

23. Stephane Vidry

International Life Sciences Institute (European Branch)

SME

Belgium (BE)

24. Jasper Scholten

Blonk Milieu Advies BV

SME

Netherlands (NL)

25. Paul Finglas

European Food Information Ress AISBL (EUROFIR)

SME

Belgium (BE)

26. Maurizio Notarfonso

SPREAD EUROPEAN SAFETY GEIE (SPES GEIE)

NPO

Italy (IT)

27. Fottes Panetsos

Bioiatriki SA

I

Greece (GR)

28. Clare Llewellyn

University College London

RI

UK (GB)

29. Alicja Szofer-Araya

European Clinical Research Infrastructure Network

NPO

France (FR)